Company Established In




Analytical Testing //

Laboratory Tablet Press

Contract / Clinical Research Services //

Contract Service Laboratory
Formulation Development
Research Services

IT / Software //


Laboratory Equipment //

Bench top equipment

Manufacturing Materials //

Solid Dosage
Tablet Presses

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Natoli Engineering Company was founded on the uncompromising principle of providing the highest quality tablet compression tooling and premium replacement parts at a fair price with exceptional customer service and unbeatable delivery times.

Natoli manufactures premium replacement parts and turrets for all makes and models of tablet presses, a diverse line of specialized, best-in-class tablet presses, and world-renowned tablet compression tooling. Additionally, Natoli provides unparalleled technical support and troubleshooting, technical training courses, and the most comprehensive tablet compression accessories catalog available today.

Natoli’s easy-to-use AIM™ Software facilitates and speeds tablet and capsule research and development and manufacturing in the pharmaceutical, nutraceutical, confectionery, and veterinary industries. And, through its Carlisle Precision Encapsulation Parts subsidiary, Natoli manufactures encapsulation change and spare parts for many brands of encapsulation machines.

Natoli’s team of expert engineers, skilled machinists, and knowledgeable customer service representatives is committed to each customer’s precise requests and to ensuring every Natoli product will perform to the highest standards. All Natoli products are backed by the same quality guarantee as their world-class tooling, and all are available for worldwide delivery.

Tablet Compression Tooling
Natoli manufactures carbide-tip, multi-tip, single-tip, 3D exotic-shape, rotating heads/tips and extended head flat punches, plus IMA Comprima tooling, lined dies, tool coatings, and more.

Tablet Presses
Natoli offers a diverse line of best-in-class tablet press options, from single-station R&D laboratory models to heavy-duty production rotary presses. Natoli production tablet presses feature AIM™ operating system instrumentation, and Natoli single-station and rotary R&D tablet presses feature AIM™ Data Acquisition and Analysis Software.

Tablet Press Replacement Parts
Natoli maintains an extensive inventory of premium tablet press replacement parts and turrets for virtually all press types, with most available for same-day shipping.

Tablet Compression Accessories Catalog
Natoli offers the most comprehensive accessories catalog in the industry, featuring hundreds of items to help care for, analyze, and prolong the life of tooling and equipment.

Encapsulation Machine Change and Spare Parts
Natoli manufactures premium encapsulation change and spare parts, from dosing discs to magazine assemblies to upper and lower segments, pins, and more. Change and spare parts are available for most encapsulation machines.

Same-Day Delivery
Many tablet press and encapsulation machine parts and accessories are in stock at Natoli service centers and available for same-day delivery. And, by allowing Natoli to manage your spare parts inventory with our Preferred Parts Program, you will reduce downtime and save money.

Tablet and Tooling Design
Natoli provides expert design services to ensure tablet quality, maximize production, and enhance product lifecycle. Natoli’s TabletCAD® Tablet Design Software, a FREE web-based software, delivers a simple way to create tablets to exact specifications with a direct link to the manufacturing process.

Natoli Scientific utilizes a network of university, consultant, and resident resources to investigate problems and offer customers unique solutions to their formulation and tooling requirements. Consultative services include formulation evaluation for sticking problems, formulation modification to improve tableting, and recommendations on coatings for abrasive and corrosive formulations. Ask Natoli Scientific for help in troubleshooting any tableting or encapsulation challenge.

Service Centers
Natoli Engineering’s service centers, located in St. Charles, Missouri; Long Island, New York; Southern California; and Szczecin, Poland, offer regional customer support with parts, accessories, tooling refurbishing, maintenance, training, and more.

Technical Training
Natoli instructors provide technical training at our St. Charles, Missouri, headquarters and at regional Natoli service centers, as well as on-site training for customers around the world. Each training event at our state-of-the-art facilities is a unique classroom and hands-on experience featuring open discussions, one-on-one consultations, Q&A, and live demonstrations.

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